Assessment of reflux symptom severity: methodological options and their attributes

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Assessment of reflux symptom severity: methodological options and their attributes.

Despite major advances in our understanding of reflux disease, the management of this disorder still presents many challenges. Reduction of heartburn is the most readily apparent objective for the patient with reflux disease. Thus the ability to measure heartburn accurately is of fundamental importance to clinical research in reflux disease. Here, the available data on the assessment of reflux ...

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Correlation Between Symptom Severity and Health-Related Life Quality of a Population With Gastroesophageal Reflux Disease

BACKGROUND Gastroesophageal reflux disease (GERD) is a chronic disease with a negative impact on the quality of life. The aim of this study was to investigate the reflux symptoms and the health-related quality of life in a population with GERD. METHODS Data from patients with GERD, according to the Montreal definition, were collected between January and December 2009. The enrolled patients we...

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Symptom severity and oesophageal chemosensitivity to acid in older and young patients with gastro-oesophageal reflux.

INTRODUCTION elderly patients appear to have a more aggressive form of gastro-oesophageal reflux disease than younger patients. Reduced pain perception with age is a possible underlying mechanism. AIMS to compare the extent of oesophageal mucosal injury, acid exposure, symptom severity and perception thresholds for acid infusion in older (aged 60 or older) and younger patients with gastro-oes...

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ژورنال

عنوان ژورنال: Gut

سال: 2004

ISSN: 0017-5749

DOI: 10.1136/gut.2003.034298